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Does Genetic Mutation Explain Why Only Some Sickle Cell Trait Athletes Suffer Exertional Sickling?

Athletes with sickle cell trait (SCT) are at increased risk of life-threatening heat stroke from a condition called exertional sickling, with heat, dehydration, asthma, high-intensity exercise and high altitude known risk factors. But why do some SCT athletes never suffer from exertional sickling or heat illness while others do (with some cases resulting in death)? A new study hopes to answer that question.
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Guidelines On Reducing, Preventing and Treating Exertional Sickling in Athletes

With the summer sports season in full swing and preparation for fall sports participation and training around the corner, it's time to revisit the guidelines for athletes with sickle cell trait.
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